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Formation of Tap/NXT1 Heterodimers Activates Tap-Dependent Nuclear mRNA Export by Enhancing Recruitment to Nuclear Pore Complexes

The Tap protein has been shown to activate the nuclear export of mRNA species bearing retroviral constitutive transport elements and is also believed to play an essential role in the sequence nonspecific export of cellular mRNAs. However, it has remained unclear how Tap activity is regulated in vivo...

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Udgivet i:Mol Cell Biol
Principais autores: Wiegand, Heather L., Coburn, Glen A., Zeng, Yan, Kang, Yibin, Bogerd, Hal P., Cullen, Bryan R.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Nucleocytoplasmic Communication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.1.245-256.2002
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