Formation of Tap/NXT1 Heterodimers Activates Tap-Dependent Nuclear mRNA Export by Enhancing Recruitment to Nuclear Pore Complexes

The Tap protein has been shown to activate the nuclear export of mRNA species bearing retroviral constitutive transport elements and is also believed to play an essential role in the sequence nonspecific export of cellular mRNAs. However, it has remained unclear how Tap activity is regulated in vivo...

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Detalhes bibliográficos
Main Authors: Wiegand, Heather L., Coburn, Glen A., Zeng, Yan, Kang, Yibin, Bogerd, Hal P., Cullen, Bryan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Nucleocytoplasmic Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134221/
https://ncbi.nlm.nih.gov/pubmed/11739738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.245-256.2002
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