PEX11α Is Required for Peroxisome Proliferation in Response to 4-Phenylbutyrate but Is Dispensable for Peroxisome Proliferator-Activated Receptor Alpha-Mediated Peroxisome Proliferation

The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes. As part of our effort to understand the molecular and physiological functions of PEX11 proteins, we disrupted the mouse PEX11α gene. Overexpression of PEX11α is sufficient to promote peroxisome division, and...

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Autors principals: Li, Xiaoling, Baumgart, Eveline, Dong, Gao-Xiang, Morrell, James C., Jimenez-Sanchez, Gerardo, Valle, David, Smith, Kirby D., Gould, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC134051/
https://ncbi.nlm.nih.gov/pubmed/12417726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8226-8240.2002
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