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Inactivation of the Retinoblastoma Protein Family Can Bypass the HCF-1 Defect in tsBN67 Cell Proliferation and Cytokinesis

Owing to a single missense mutation in the cell proliferation factor HCF-1, the temperature-sensitive tsBN67 hamster cell line arrests proliferation at nonpermissive temperatures, primarily in a G(0)/G(1) state, and displays temperature-sensitive cytokinesis defects. The HCF-1 mutation in tsBN67 cel...

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Bibliografiske detaljer
Main Authors: Reilly, Patrick T., Wysocka, Joanna, Herr, Winship
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC134044/
https://ncbi.nlm.nih.gov/pubmed/12215534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6767-6778.2002
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