Transketolase Haploinsufficiency Reduces Adipose Tissue and Female Fertility in Mice
Transketolase (TKT) is a ubiquitous enzyme used in multiple metabolic pathways. We show here by gene targeting that TKT-null mouse embryos are not viable and that disruption of one TKT allele can cause growth retardation (≈35%) and preferential reduction of adipose tissue (≈77%). Other TKT(+/−) tiss...
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| Wydane w: | Mol Cell Biol |
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| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
2002
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12167708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.17.6142-6147.2002 |
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