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Multiple Phosphoinositide 3-Kinase-Dependent Steps in Activation of Protein Kinase B

The protein kinase B (PKB)/Akt family of serine kinases is rapidly activated following agonist-induced stimulation of phosphoinositide 3-kinase (PI3K). To probe the molecular events important for the activation process, we employed two distinct models of posttranslational inducible activation and me...

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Библиографические подробности
Главные авторы: Scheid, Michael P., Marignani, Paola A., Woodgett, James R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC134003/
https://ncbi.nlm.nih.gov/pubmed/12167717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6247-6260.2002
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