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The Zinc Finger Domain of NEMO Is Selectively Required for NF-κB Activation by UV Radiation and Topoisomerase Inhibitors

Exposure of mammalian cells to UV radiation was proposed to stimulate the transcription factor NF-κB by a unique mechanism. Typically, rapid and strong inducers of NF-κB, such as tumor necrosis factor alpha (TNF-α) and bacterial lipopolysaccharide (LPS), lead to rapid phosphorylation and proteasomal...

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Autori principali: Huang, Tony T., Feinberg, Shelby L., Suryanarayanan, Sainath, Miyamoto, Shigeki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC133970/
https://ncbi.nlm.nih.gov/pubmed/12138192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.16.5813-5825.2002
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