Testis-Specific Cytochrome c-Null Mice Produce Functional Sperm but Undergo Early Testicular Atrophy

Differentiating male germ cells express a testis-specific form of cytochrome c (Cyt c(T)) that is distinct from the cytochrome c expressed in somatic cells (Cyt c(S)). To examine the role of Cyt c(T) in germ cells, we generated mice null for Cyt c(T). Homozygous Cyt c(T)(−/−) pups were statistically...

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Detalhes bibliográficos
Main Authors: Narisawa, Sonoko, Hecht, Norman B., Goldberg, Erwin, Boatright, Kelly M., Reed, John C., Millán, José Luis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133957/
https://ncbi.nlm.nih.gov/pubmed/12101247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5554-5562.2002
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