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Nuclear Export of mRNA by TAP/NXF1 Requires Two Nucleoporin-Binding Sites but Not p15

Metazoan NXF1/p15 heterodimers promote export of bulk mRNA through nuclear pore complexes (NPC). NXF1 interacts with the NPC via two distinct structural domains, the UBA-like domain and the NTF2-like scaffold, which results from the heterodimerization of the NTF2-like domain of NXF1 with p15. Both d...

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Publicado no:Mol Cell Biol
Principais autores: Braun, Isabelle C., Herold, Andrea, Rode, Michaela, Izaurralde, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2002
Assuntos:
Nucleocytoplasmic Communication
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12101235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.15.5405-5418.2002
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