Distinct Cellular Functions of MK2

Mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) is activated upon stress by p38 MAPKα and -β, which bind to a basic docking motif in the C terminus of MK2 and which subsequently phosphorylate its regulatory sites. As a result of activation MK2 is exported from the nucleus to...

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Bibliographic Details
Main Authors: Kotlyarov, Alexey, Yannoni, Yvonne, Fritz, Susann, Laaß, Kathrin, Telliez, Jean-Baptiste, Pitman, Deborah, Lin, Lih-Ling, Gaestel, Matthias
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133920/
https://ncbi.nlm.nih.gov/pubmed/12052889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4827-4835.2002
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