Replication and Subnuclear Location Dynamics of the Immunoglobulin Heavy-Chain Locus in B-Lineage Cells

The murine immunoglobulin heavy-chain (Igh) locus provides an important model for understanding the replication of tissue-specific gene loci in mammalian cells. We have observed two DNA replication programs with dramatically different temporal replication patterns for the Igh locus in B-lineage cell...

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Detalhes bibliográficos
Main Authors: Zhou, Jie, Ermakova, Olga V., Riblet, Roy, Birshtein, Barbara K., Schildkraut, Carl L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133899/
https://ncbi.nlm.nih.gov/pubmed/12052893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4876-4889.2002
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