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Conserved Sequences in a Tissue-Specific Regulatory Region of the pdx-1 Gene Mediate Transcription in Pancreatic β Cells: Role for Hepatocyte Nuclear Factor 3β and Pax6
Pancreas duodenum homeobox 1 (PDX-1) is absolutely required for pancreas development and the maintenance of islet β-cell function. Temporal and cell-type-specific transcription of the pdx-1 gene is controlled by factors acting upon sequences found within its 5′-flanking region. Critical cis-acting t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133887/ https://ncbi.nlm.nih.gov/pubmed/12052878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4702-4713.2002 |
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