Constitutive Association of BRCA1 and c-Abl and Its ATM-Dependent Disruption after Irradiation

BRCA1 plays an important role in mechanisms of response to double-strand breaks, participating in genome surveillance, DNA repair, and cell cycle checkpoint arrests. Here, we identify a constitutive BRCA1-c-Abl complex and provide evidence for a direct interaction between the PXXP motif in the C ter...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Foray, Nicolas, Marot, Didier, Randrianarison, Voahangy, Dalla Venezia, Nicole, Picard, Didier, Perricaudet, Michel, Favaudon, Vincent, Jeggo, Penny
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2002
Soggetti:	Transcriptional Regulation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133860/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12024016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.12.4020-4032.2002
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