APS Facilitates c-Cbl Tyrosine Phosphorylation and GLUT4 Translocation in Response to Insulin in 3T3-L1 Adipocytes

APS is a Cbl-binding protein that is tyrosine phosphorylated by the insulin receptor kinase. Insulin-stimulated phosphorylation of tyrosine 618 in APS is necessary for its association with c-Cbl and the subsequent tyrosine phosphorylation of Cbl by the insulin receptor in both 3T3-L1 adipocytes and...

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Bibliographic Details
Main Authors: Liu, Jun, Kimura, Akiko, Baumann, Christian A., Saltiel, Alan R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133825/
https://ncbi.nlm.nih.gov/pubmed/11997497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3599-3609.2002
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