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Multiple Nucleosome Positioning Sites Regulate the CTCF-Mediated Insulator Function of the H19 Imprinting Control Region†

The 5′ region of the H19 gene harbors a methylation-sensitive chromatin insulator within an imprinting control region (ICR). Insertional mutagenesis in combination with episomal assays identified nucleosome positioning sequences (NPSs) that set the stage for the remarkably precise distribution of th...

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Udgivet i:Mol Cell Biol
Principais autores: Kanduri, Meena, Kanduri, Chandrasekhar, Mariano, Piero, Vostrov, Alexander A., Quitschke, Wolfgang, Lobanenkov, Victor, Ohlsson, Rolf
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11971967/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.10.3339-3344.2002
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