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Multiple Nucleosome Positioning Sites Regulate the CTCF-Mediated Insulator Function of the H19 Imprinting Control Region†

The 5′ region of the H19 gene harbors a methylation-sensitive chromatin insulator within an imprinting control region (ICR). Insertional mutagenesis in combination with episomal assays identified nucleosome positioning sequences (NPSs) that set the stage for the remarkably precise distribution of th...

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Autori principali: Kanduri, Meena, Kanduri, Chandrasekhar, Mariano, Piero, Vostrov, Alexander A., Quitschke, Wolfgang, Lobanenkov, Victor, Ohlsson, Rolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC133793/
https://ncbi.nlm.nih.gov/pubmed/11971967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.10.3339-3344.2002
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