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Multiple Nucleosome Positioning Sites Regulate the CTCF-Mediated Insulator Function of the H19 Imprinting Control Region†

The 5′ region of the H19 gene harbors a methylation-sensitive chromatin insulator within an imprinting control region (ICR). Insertional mutagenesis in combination with episomal assays identified nucleosome positioning sequences (NPSs) that set the stage for the remarkably precise distribution of th...

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Detalhes bibliográficos
Main Authors: Kanduri, Meena, Kanduri, Chandrasekhar, Mariano, Piero, Vostrov, Alexander A., Quitschke, Wolfgang, Lobanenkov, Victor, Ohlsson, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133793/
https://ncbi.nlm.nih.gov/pubmed/11971967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.10.3339-3344.2002
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