Initiation Sites Are Distributed at Frequent Intervals in the Chinese Hamster Dihydrofolate Reductase Origin of Replication but Are Used with Very Different Efficiencies

Previous radiolabeling and two-dimensional (2-D) gel studies of the dihydrofolate reductase (DHFR) domain of Chinese hamster cells have suggested that replication can initiate at any one of a very large number of inefficient sites scattered throughout the 55-kb intergenic spacer region, with two bro...

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Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Dijkwel, Pieter A., Wang, Shuntai, Hamlin, Joyce L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2002
Schlagworte:	DNA Dynamics and Chromosome Structure
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11940663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.9.3053-3065.2002
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