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The Direct Recruitment of BLNK to Immunoglobulin α Couples the B-Cell Antigen Receptor to Distal Signaling Pathways
Following B-cell antigen receptor (BCR) ligation, the cytoplasmic domains of immunoglobulin α (Igα) and Igβ recruit Syk to initiate signaling cascades. The coupling of Syk to several distal substrates requires linker protein BLNK. However, the mechanism by which BLNK is recruited to the BCR is unkno...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133735/ https://ncbi.nlm.nih.gov/pubmed/11909947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2524-2535.2002 |
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