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Fission Yeast Mad3p Is Required for Mad2p To Inhibit the Anaphase-Promoting Complex and Localizes to Kinetochores in a Bub1p-, Bub3p-, and Mph1p-Dependent Manner

The spindle checkpoint delays the metaphase-to-anaphase transition in response to spindle and kinetochore defects. Genetic screens in budding yeast identified the Mad and Bub proteins as key components of this conserved regulatory pathway. Here we present the fission yeast homologue of Mad3p. Cells...

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Détails bibliographiques
Auteurs principaux: Millband, David N., Hardwick, Kevin G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC133725/
https://ncbi.nlm.nih.gov/pubmed/11909965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2728-2742.2002
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