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Fission Yeast Mad3p Is Required for Mad2p To Inhibit the Anaphase-Promoting Complex and Localizes to Kinetochores in a Bub1p-, Bub3p-, and Mph1p-Dependent Manner

The spindle checkpoint delays the metaphase-to-anaphase transition in response to spindle and kinetochore defects. Genetic screens in budding yeast identified the Mad and Bub proteins as key components of this conserved regulatory pathway. Here we present the fission yeast homologue of Mad3p. Cells...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Millband, David N., Hardwick, Kevin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133725/
https://ncbi.nlm.nih.gov/pubmed/11909965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2728-2742.2002
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