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Autoinhibitory Regulation of p73 by ΔNp73 To Modulate Cell Survival and Death through a p73-Specific Target Element within the ΔNp73 Promoter
p73 is a p53-related tumor suppressor but is also induced by oncogene products such as E2F-1, raising a question as to whether p73 is a tumor suppressor gene or oncogene. Unlike p53, p73 has several variants, including ΔNp73, which lacks the NH(2)-terminal transactivation domain. Although, in develo...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2002
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133713/ https://ncbi.nlm.nih.gov/pubmed/11909952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2575-2585.2002 |
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