Stat1-Vitamin D Receptor Interactions Antagonize 1,25-Dihydroxyvitamin D Transcriptional Activity and Enhance Stat1-Mediated Transcription

The cytokine gamma interferon (IFN-γ) and the calcitropic steroid hormone 1,25-dihydroxyvitamin D (1,25D) are activators of macrophage immune function. In sarcoidosis, tuberculosis, and several granulomatoses, IFN-γ induces 1,25D synthesis by macrophages and inhibits 1,25D induction of 24-hydroxylas...

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Detalhes bibliográficos
Main Authors: Vidal, Marcos, Ramana, Chilakamarti V., Dusso, Adriana S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133712/
https://ncbi.nlm.nih.gov/pubmed/11909970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2777-2787.2002
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