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The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D(3)

The vitamin D receptor (VDR) is a critical mediator of the biological actions of 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). As a nuclear receptor, ligand activation of the VDR leads to the protein’s binding to specific sites on the genome that results in the modulation of target gene expression....

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Pubblicato in:J Steroid Biochem Mol Biol
Autori principali: Lee, Seong Min, Pike, J. Wesley
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769962/
https://ncbi.nlm.nih.gov/pubmed/26323657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2015.08.018
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