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The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D(3)
The vitamin D receptor (VDR) is a critical mediator of the biological actions of 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). As a nuclear receptor, ligand activation of the VDR leads to the protein’s binding to specific sites on the genome that results in the modulation of target gene expression....
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| Published in: | J Steroid Biochem Mol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4769962/ https://ncbi.nlm.nih.gov/pubmed/26323657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2015.08.018 |
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