Functional Divergence between Histone Deacetylases in Fission Yeast by Distinct Cellular Localization and In Vivo Specificity

Histone deacetylases (HDACs) are important for gene regulation and the maintenance of heterochromatin in eukaryotes. Schizosaccharomyces pombe was used as a model system to investigate the functional divergence within this conserved enzyme family. S. pombe has three HDACs encoded by the hda1(+), clr...

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Библиографические подробности
Главные авторы: Bjerling, Pernilla, Silverstein, Rebecca A., Thon, Geneviève, Caudy, Amy, Grewal, Shiv, Ekwall, Karl
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
DNA Dynamics and Chromosome Structure
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC133699/
https://ncbi.nlm.nih.gov/pubmed/11884604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2170-2181.2002
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