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Functional Divergence between Histone Deacetylases in Fission Yeast by Distinct Cellular Localization and In Vivo Specificity

Histone deacetylases (HDACs) are important for gene regulation and the maintenance of heterochromatin in eukaryotes. Schizosaccharomyces pombe was used as a model system to investigate the functional divergence within this conserved enzyme family. S. pombe has three HDACs encoded by the hda1(+), clr...

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Udgivet i:Mol Cell Biol
Principais autores: Bjerling, Pernilla, Silverstein, Rebecca A., Thon, Geneviève, Caudy, Amy, Grewal, Shiv, Ekwall, Karl
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133699/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884604/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.7.2170-2181.2002
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