Partial Reconstitution of Human DNA Mismatch Repair In Vitro: Characterization of the Role of Human Replication Protein A

DNA mismatch repair (MMR) is a critical genome-stabilization system. However, the molecular mechanism of MMR in human cells remains obscure because many of the components have not yet been identified. Using a functional in vitro reconstitution system, this study identified three HeLa cell fractions...

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Detalhes bibliográficos
Main Authors: Ramilo, Cecilia, Gu, Liya, Guo, Shuangli, Zhang, Xiping, Patrick, Steve M., Turchi, John J., Li, Guo-Min
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133689/
https://ncbi.nlm.nih.gov/pubmed/11884592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2037-2046.2002
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