Involvement of Mouse Rev3 in Tolerance of Endogenous and Exogenous DNA Damage

The Rev3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase ζ that is implicated in mutagenic translesion synthesis of damaged DNA. To investigate the function of its mouse homologue, we have generated mouse embryonic stem cells and mice carrying a targeted disruption o...

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Detalhes bibliográficos
Main Authors: Van Sloun, Petra P. H., Varlet, Isabelle, Sonneveld, Edwin, Boei, Jan J. W. A., Romeijn, Ron J., Eeken, Jan C. J., De Wind, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133679/
https://ncbi.nlm.nih.gov/pubmed/11884603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2159-2169.2002
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