Protein Phosphatase 2A Forms a Molecular Complex with Shc and Regulates Shc Tyrosine Phosphorylation and Downstream Mitogenic Signaling

Protein phosphatase 2A (PP2A) is a multimeric serine/threonine phosphatase that carries out multiple functions. Although numerous observations suggest that PP2A plays a major role in downregulation of the mitogen-activated protein (MAP) kinase pathway, the precise mechanisms are unknown. To clarify...

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Detalhes bibliográficos
Main Authors: Ugi, Satoshi, Imamura, Takeshi, Ricketts, William, Olefsky, Jerrold M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133677/
https://ncbi.nlm.nih.gov/pubmed/11884620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2375-2387.2002
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