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Protein Phosphatase 2A Forms a Molecular Complex with Shc and Regulates Shc Tyrosine Phosphorylation and Downstream Mitogenic Signaling

Protein phosphatase 2A (PP2A) is a multimeric serine/threonine phosphatase that carries out multiple functions. Although numerous observations suggest that PP2A plays a major role in downregulation of the mitogen-activated protein (MAP) kinase pathway, the precise mechanisms are unknown. To clarify...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Ugi, Satoshi, Imamura, Takeshi, Ricketts, William, Olefsky, Jerrold M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133677/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.7.2375-2387.2002
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