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Nucleocytoplasmic Distribution of Human RNA-editing Enzyme ADAR1 Is Modulated by Double-stranded RNA-binding Domains, a Leucine-rich Export Signal, and a Putative Dimerization Domain

The human RNA-editing enzyme adenosine deaminase that acts on RNA (ADAR1) is expressed in two versions. A longer 150-kDa protein is interferon inducible and can be found both in the nucleus and cytoplasm. An amino-terminally truncated 110-kDa version, in contrast, is constitutively expressed and pre...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Principais autores: Strehblow, Alexander, Hallegger, Martina, Jantsch, Michael F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133595/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12429827/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-03-0161
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