Structure of the major single-stranded DNA-binding domain of replication protein A suggests a dynamic mechanism for DNA binding

Although structures of single-stranded (ss)DNA-binding proteins (SSBs) have been reported with and without ssDNA, the mechanism of ssDNA binding in eukarya remains speculative. Here we report a 2.5 Å structure of the ssDNA-binding domain of human replication protein A (RPA) (eukaryotic SSB), for whi...

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Bibliographic Details

Published in:	EMBO J
Main Authors:	Bochkareva, Elena, Belegu, Visar, Korolev, Sergey, Bochkarev, Alexey
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2001
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11157767/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.3.612
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