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Structure of the major single-stranded DNA-binding domain of replication protein A suggests a dynamic mechanism for DNA binding
Although structures of single-stranded (ss)DNA-binding proteins (SSBs) have been reported with and without ssDNA, the mechanism of ssDNA binding in eukarya remains speculative. Here we report a 2.5 Å structure of the ssDNA-binding domain of human replication protein A (RPA) (eukaryotic SSB), for whi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133470/ https://ncbi.nlm.nih.gov/pubmed/11157767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.3.612 |
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