Splicing and 3′ end formation in the definition of nonsense-mediated decay-competent human β-globin mRNPs
Premature translation termination codons are common causes of genetic disorders. mRNAs with such mutations are degraded by a surveillance mechanism termed nonsense-mediated decay (NMD), which represents a phylogenetically widely conserved post-transcriptional mechanism for the quality control of gen...
Kaydedildi:
| Yayımlandı: | EMBO J |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11157759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.3.532 |
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