Role of Caspase 1 in Murine Antibacterial Host Defenses and Lethal Endotoxemia

Sepsis is thought to result from an exaggerated innate immune response to microbial components such as lipopolysaccharide (LPS), but the involvement of a specific mechanism(s) has not been identified. We studied the role of caspase 1 (Cas-1) in the murine innate immune response to infection with gra...

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Autors principals: Joshi, Vishwas D., Kalvakolanu, Dhananjaya V., Hebel, John R., Hasday, Jeffrey D., Cross, Alan S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC133093/
https://ncbi.nlm.nih.gov/pubmed/12438367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6896-6903.2002
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