Role of Caspase 1 in Murine Antibacterial Host Defenses and Lethal Endotoxemia

Sepsis is thought to result from an exaggerated innate immune response to microbial components such as lipopolysaccharide (LPS), but the involvement of a specific mechanism(s) has not been identified. We studied the role of caspase 1 (Cas-1) in the murine innate immune response to infection with gra...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Joshi, Vishwas D., Kalvakolanu, Dhananjaya V., Hebel, John R., Hasday, Jeffrey D., Cross, Alan S.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Host Response and Inflammation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.12.6896-6903.2002
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