Immunization with the N-Terminal Portion of Treponema pallidum Repeat Protein K Attenuates Syphilitic Lesion Development in the Rabbit Model

When used as an immunogen, Treponema pallidum repeat protein K (TprK) has been shown to attenuate syphilitic lesions upon homologous intradermal challenge in the rabbit model. To further explore this protein as a potential vaccine component, we sought to identify the immunogenic regions of TprK. The...

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Bibliographic Details
Main Authors: Morgan, Cecilia A., Lukehart, Sheila A., Van Voorhis, Wesley C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133068/
https://ncbi.nlm.nih.gov/pubmed/12438357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6811-6816.2002
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