Immunization with the N-Terminal Portion of Treponema pallidum Repeat Protein K Attenuates Syphilitic Lesion Development in the Rabbit Model

When used as an immunogen, Treponema pallidum repeat protein K (TprK) has been shown to attenuate syphilitic lesions upon homologous intradermal challenge in the rabbit model. To further explore this protein as a potential vaccine component, we sought to identify the immunogenic regions of TprK. The...

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Pubblicato in:	Infect Immun
Autori principali:	Morgan, Cecilia A., Lukehart, Sheila A., Van Voorhis, Wesley C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.12.6811-6816.2002
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