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Development of Interleukin-12-Producing Capacity throughout Childhood
Increasing evidence indicates that the capacity to induce protective Th1 immune responses is impaired in early childhood, an observation that can be partially attributed to deficiencies in antigen-presenting-cell function. Synthesis of interleukin 12 (IL-12), a key Th1-trophic cytokine, is markedly...
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Main Authors: | Upham, John W., Lee, Peter T., Holt, Barbara J., Heaton, Tricia, Prescott, Susan L., Sharp, Mary J., Sly, Peter D., Holt, Patrick G. |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133015/ https://ncbi.nlm.nih.gov/pubmed/12438328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6583-6588.2002 |
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