Development of Interleukin-12-Producing Capacity throughout Childhood

Increasing evidence indicates that the capacity to induce protective Th1 immune responses is impaired in early childhood, an observation that can be partially attributed to deficiencies in antigen-presenting-cell function. Synthesis of interleukin 12 (IL-12), a key Th1-trophic cytokine, is markedly...

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Detalhes bibliográficos
Main Authors: Upham, John W., Lee, Peter T., Holt, Barbara J., Heaton, Tricia, Prescott, Susan L., Sharp, Mary J., Sly, Peter D., Holt, Patrick G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133015/
https://ncbi.nlm.nih.gov/pubmed/12438328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6583-6588.2002
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