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Relationships of agonist properties to the single channel kinetics of nicotinic acetylcholine receptors.

The effects of the systematic variations of the acetylcholine molecule on the microscopic kinetics of channel activation were studied using the patch clamp technique. The modifications consisted of adding either halogens or a methyl group to the acetyl carbon of acetylcholine, which results in a cha...

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Autors principals: Papke, R L, Millhauser, G, Lieberman, Z, Oswald, R E
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1330115/
https://ncbi.nlm.nih.gov/pubmed/2449251
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