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Enhanced Immunogenicity of a Genetic Chimeric Protein Consisting of Two Virulence Antigens of Streptococcus mutans and Protection against Infection

The saliva-binding region (SBR) of the cell surface antigen I/II (AgI/II) and the glucan-binding region (GLU) of the glucosyltransferase enzyme of Streptococcus mutans have been implicated in the initial adherence of S. mutans to saliva-coated tooth surfaces and the subsequent sucrose-dependent accu...

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Bibliografiske detaljer
Main Authors: Zhang, Ping, Jespersgaard, Christina, Lamberty-Mallory, Leticia, Katz, Jannet, Huang, Yan, Hajishengallis, George, Michalek, Suzanne M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133010/
https://ncbi.nlm.nih.gov/pubmed/12438353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6779-6787.2002
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