Decreased Infectivity despite Unaltered C3 Binding by a ΔhbhA Mutant of Mycobacterium tuberculosis

HbhA of Mycobacterium tuberculosis is a multifunctional binding protein, binding to both sulfated sugars such as heparin and to human complement component C3. HbhA may therefore interact with host molecules and/or host cells during M. tuberculosis infection and play a role in the pathogenesis of thi...

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Detalhes bibliográficos
Main Authors: Mueller-Ortiz, Stacey L., Sepulveda, Eliud, Olsen, Margaret R., Jagannath, Chinnaswamy, Wanger, Audrey R., Norris, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133004/
https://ncbi.nlm.nih.gov/pubmed/12438350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6751-6760.2002
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