Chromosomal DNA Deletions Explain Phenotypic Characteristics of Two Antigenic Variants, Phase II and RSA 514 (Crazy), of the Coxiella burnetii Nine Mile Strain†

After repeated passages through embyronated eggs, the Nine Mile strain of Coxiella burnetii exhibits antigenic variation, a loss of virulence characteristics, and transition to a truncated lipopolysaccharide (LPS) structure. In two independently derived strains, Nine Mile phase II and RSA 514, these...

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Main Authors: Hoover, T. A., Culp, D. W., Vodkin, M. H., Williams, J. C., Thompson, H. A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Molecular Pathogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC132984/
https://ncbi.nlm.nih.gov/pubmed/12438347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6726-6733.2002
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