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The Attenuated Nine Mile Phase II Clone 4/RSA439 Strain of Coxiella burnetii Is Highly Virulent for Severe Combined Immunodeficient (SCID) Mice
The Nine Mile phase II clone 4 (NMIIC4) strain of Coxiella burnetii is an attenuated phase II strain that has lost the genes for virulence determinant type 1 lipopolysaccharide. These bacteria were very virulent for severe combined immunodeficient (SCID) mice. The lethal dose 50 (LD(50)) was ∼10 bac...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Tropical Medicine and Hygiene
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795117/ https://ncbi.nlm.nih.gov/pubmed/23958905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.12-0653 |
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