Rough Lipopolysaccharide from Brucella abortus and Escherichia coli Differentially Activates the Same Mitogen-Activated Protein Kinase Signaling Pathways for Tumor Necrosis Factor Alpha in RAW 264.7 Macrophage-Like Cells

The intracellular, gram-negative pathogen Brucella abortus establishes chronic infections in host macrophages while downregulating cytokines such as tumor necrosis factor alpha (TNF-α). When producing TNF-α, Brucella abortus rough lipopolysaccharide (LPS) activates the same mitogen-activated protein...

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Détails bibliographiques

Publié dans:	Infect Immun
Auteurs principaux:	Jarvis, Bruce W., Harris, Tajie H., Qureshi, Nilofer, Splitter, Gary A.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438403/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.12.7165-7168.2002
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