Rough Lipopolysaccharide from Brucella abortus and Escherichia coli Differentially Activates the Same Mitogen-Activated Protein Kinase Signaling Pathways for Tumor Necrosis Factor Alpha in RAW 264.7 Macrophage-Like Cells

The intracellular, gram-negative pathogen Brucella abortus establishes chronic infections in host macrophages while downregulating cytokines such as tumor necrosis factor alpha (TNF-α). When producing TNF-α, Brucella abortus rough lipopolysaccharide (LPS) activates the same mitogen-activated protein...

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Detalhes bibliográficos
Main Authors: Jarvis, Bruce W., Harris, Tajie H., Qureshi, Nilofer, Splitter, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC132973/
https://ncbi.nlm.nih.gov/pubmed/12438403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.7165-7168.2002
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