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Virulence Criteria for Brucella abortus Strains as Determined by Interferon Regulatory Factor 1-Deficient Mice
Interferon regulatory factor 1-deficient (IRF-1(−/−)) mice infected with virulent Brucella abortus 2308 at 5 × 10(5) CFU developed acute hepatitis similar to many natural hosts but, unlike natural hosts, IRF-1(−/−) mice were unable to resolve infection and died. In contrast, IRF-1(−/−) mice survived...
में बचाया:
| मुख्य लेखकों: | , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Microbiology
2002
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC132959/ https://ncbi.nlm.nih.gov/pubmed/12438380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.7004-7012.2002 |
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