The Function of Gamma Interferon-Inducible GTP-Binding Protein IGTP in Host Resistance to Toxoplasma gondii Is Stat1 Dependent and Requires Expression in Both Hematopoietic and Nonhematopoietic Cellular Compartments

IGTP is a member of the 47-kDa family of gamma interferon (IFN-γ)-induced GTPases. We have previously shown that IGTP is critical for host resistance to Toxoplasma gondii infection. In the present study, we demonstrate that T. gondii-induced IGTP expression in vivo and IFN-γ-driven synthesis of the...

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Pubblicato in:	Infect Immun
Autori principali:	Collazo, Carmen M., Yap, George S., Hieny, Sara, Caspar, Patricia, Feng, Carl G., Taylor, Gregory A., Sher, Alan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438372/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.12.6933-6939.2002
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