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Antibodies selected from combinatorial libraries block a tumor antigen that plays a key role in immunomodulation
We searched for cell-surface-associated proteins overexpressed on B cell chronic lymphocytic leukemia (CLL) to use as therapeutic antibody targets. Antibodies binding the immunosuppressive molecule CD200 were identified by cell panning of an antibody phage display library derived from rabbits immuni...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1327729/ https://ncbi.nlm.nih.gov/pubmed/16418292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510081103 |
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