Coadministration of Indinavir and Nelfinavir in Human Immunodeficiency Virus Type 1-Infected Adults: Safety, Pharmacokinetics, and Antiretroviral Activity

Combinations of protease inhibitors (PIs) can have potentially beneficial pharmacokinetic interactions, resulting in higher drug levels and less frequent dose administration. Indinavir (IDV) and nelfinavir (NFV) are potent inhibitors of human immunodeficiency virus type 1 (HIV-1) protease and are co...

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Bibliographic Details
Main Authors: Riddler, Sharon A., Havlir, Diane, Squires, Kathleen E., Kerr, Brad, Lewis, Ronald H., Yeh, Kuang, Wynne, Linda Hawe, Zhong, Ling, Peng, Yahong, Deutsch, Paul, Saah, Alfred
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC132738/
https://ncbi.nlm.nih.gov/pubmed/12435691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.3877-3882.2002
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