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AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1

The R-SNARE VAMP4, which contains a dileucine motif, binds to the AP-1 (adaptor protein-1) subunit μ1a, but not μ1b, or the GGAs (Golgi-associated gamma ear containing ARF binding proteins). Serine 20 and leucines 25,26 are essential for this binding. AP-1 association with VAMP4 is enhanced when ser...

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Autores principales: Hinners, Ina, Wendler, Franz, Fei, Hao, Thomas, Laurel, Thomas, Gary, Tooze, Sharon A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326413/
https://ncbi.nlm.nih.gov/pubmed/14608369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400018
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